Wang Lab @ UNC Chapel Hill

Department of Genetics
Center for Gastrointestinal Biology and Disease
Bioinformatics and Computational Biology

 


Research

Our research focuses on metagenomics and long-read (single-molecule) informatics. We develop novel methods to enable more efficient *omic analysis and apply carefully architected high-performance computing approaches to improve the utility of genomics in studies of human disease.

Metagenomics and metataxonomics

On mucosally-associated microbiota in inflammatory bowel disease

Single-molecule sequencing of metagenomes produces more specific taxonomic and genic characterization than standard NGS, but challenges remain due to relatively low throughput and high error rate, particularly from host-associated microbial communities. We have developed novel sequencing and informatics approaches to increase throughput and classification accuracy in both synthetic and human tissue-associated microbiota.

Wang et al. 2021. Shahir et al. 2020.

Pediatric cancer classification

Using full-length (long-read) transcriptomics

Zhao et al. 2020. Wang et al. 2022.

Genomic epidemiology

Also mostly using nanopore sequencing

Multi-drug-resistant E. coli; P. aeruginosa and S. aureus in cystic fibrosis; SARS-CoV-2 genomic surveillance.

Wang et al. 2022. Tegha et al. 2020.

People

Jeremy Wang, Ph.D.

PI

I am an Assistant Professor in the Department of Genetics.

Office: 308 Fordham Hall


John Lin

Ph.D. student

John is a 1st year Ph.D. student in the Curriculum for Bioinformatics and Computational Biology.

Office: 3001 Genome Sciences Building


Bryson Deanhardt, Ph.D.

Postdoc

Bryson is a postdoc who joined the lab in 2021 after completing his Ph.D. at Duke.

Office: 3001 Genome Sciences Building


Prospective students & postdocs

Graduate students are admitted through the Biological & Biomedical Sciences Program, through which you may join any number of labs, including ours.

Prospective postdocs should email their CV to [ jeremy @ unc ⋅ edu ].


Contact

GSB

Lab: 3144 Genome Sciences Building
Ph: 919 886 4006
Email: jeremy @ unc ⋅ edu